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One day after completing its acquisition of Warner Bros. Discovery, Skydance leadership acknowledged the inevitable consequence of combining two of Hollywood’s largest entertainment companies under $80 billion of debt. Significant layoffs are on the way.

In a memo to employees, chairman and CEO David Ellison and co-CEO Ynon Kreiz warned that integrating the companies would require “difficult decisions that affect our workforce,” while promising to handle the process “thoughtfully and respectfully.”

The warning comes as little surprise. Skydance has committed to extracting at least $6 billion in annual cost savings within three years, while insisting those savings won’t require reducing studio content budgets.

During its pursuit of Warner Bros. Discovery, Skydance identified overlapping corporate, legal, technology, and infrastructure operations as areas where it could eliminate costs. That is the familiar arithmetic of a merger of this scale.

Meanwhile, any relief over Warner Bros. Discovery CEO David Zaslav’s departure may be tempered by the arrival of former Activision Blizzard CEO and mustache-twirling cartoon villain Bobby Kotick on the company’s board. Kotick’s disastrous tenure at the video game giant was marked by mass layoffs and workplace misconduct controversies. Former British prime minister Tony Blair has also joined as an advisor.

For employees, the uncertainty is only beginning. Integrating the companies will take time, and Skydance’s promised savings suggest this week’s warning is unlikely to be the last difficult workforce announcement to emerge from the process.

Pictured at top: The Looney Tunes Show, “Working Duck”